High-speed train industry is in the stage of rapid development, and the reliability allocation strategy is helpful to improve the reliability of the system and reduce the economic cost of components. In this paper, the reliability allocation of gearbox transmission system of highspeed train is studied. Combining AGREE allocation method and reliability allocation method based on cost function, the reliability allocation of high-speed train gear transmission system is carried out. Considering the quantity, importance, cost and complexity of various parts of high-speed train gear transmission system, the feasibility factor of improving reliability based on the cost function allocation method was improved to acquire the improved cost function, and the reliability optimization allocation model based on the improved cost function was established. Compared with AGREE allocation method and the traditional allocation method based on cost function, the improved optimization allocation strategy proposed in this paper is more suitable for high-speed train gear transmission system.